Searchable abstracts of presentations at key conferences in endocrinology

ea0092op-05-02 | Oral Session 5: Young Investigators / Basic | ETA2023

Thyroid tumor microenvironment: deconvolution of tumor composition using DNA methylation data

Rodriguez-Lloveras Helena , Carmela Iglesias , Klein Hesselink Esther , Lluis Reverter Jordi , Links Thera , Carles Zafon , Jorda Mireia

Introduction: Most thyroid cancer (TC) patients have a good prognosis, but some of them show aggressive behavior and are resistant to treatment. Still no effective biomarkers are available to predict which patients will progress. Epigenetic alterations are a hallmark of cancer, and profiling DNA methylation has allowed a better understanding of the epigenetic landscape of TC and its influence in TC progression. However, bulk DNA methylomes include information not only from tum...